The LRRC8A Antibody (C-term) from MyBioSource.com is a Rabbit Polyclonal antibody to LRRC8, and LRRC8A. This antibody recognizes Human, and Rat antigen. The LRRC8A Antibody (C-term) has been validated for the following applications: ELISA, and Western Blot.
Description
This gene encodes a protein belonging to the leucine-rich
repeat family of proteins, which are involved in diverse biological
processes, including cell adhesion, cellular trafficking, and
hormone-receptor interactions. This family member is a putative
four-pass transmembrane protein that plays a role in B cell
development. Defects in this gene cause autosomal dominant
non-Bruton type agammaglobulinemia, an immunodeficiency disease
resulting from defects in B cell maturation. Multiple alternatively
spliced transcript variants, which encode the same protein, have
been identified for this gene